Faculties and centres
Biochemistry I is a basic training course of the Degree in Biology which has a main aim that is to provide a general view of the most important biomolecules found in nature, as well as to establish the chemical, molecular and genetic basis of the biological processes. Through the history of this scientific discipline, the biochemists have worked to reveal the chemical and physical principles that support the biological processes. Therefore, Biochemistry establishes the knowledge basis to be able to identify these processes. This course provides the basis both for the comprehension of other courses of the Degree as well as for the development of the future career of the graduate in Biology.
Generic Degree Course Competences
Specific Competences:>> Ability
Generic UA Competences
-To know the structure and function of the different biomolecules and to understand their function in the biological processes.
- To know the fundamentals of the replication, transcription and translation of the genetic material.
- To interpret, evaluate process and synthesise information of biochemistry and molecular biology data.
- To acquire basic skills to experiment and to interpret the information proceeding from observation and measurement in biochemistry and molecular biology, using the biological material, reagents, instruments and application devices in a safe way.
- To be able to seek, to analyse and to understand scientific texts of Biochemistry and molecular biology.
- To use correctly inductive and deductive methods in the field of biochemistry and molecular biology.
- To recognise and value the biochemical processes in the daily life.
- To relate biochemistry and molecular biology to other subjects.
- To offer a view of the concept of biochemistry and to set up the axioms of the molecular logic of the cells.
- To describe the physical and chemical properties of water, as the most abundant compound within the cell.
- To state the laws of thermodynamic and to set up the relations among the different state functions.
- To know the role that ATP plays in the energetic metabolism.
- To solve acid - base problems involving amino acids, to estimate the isoelectric points and net charges, and to draw and to understand their pH titration curves.
- To apply the basic essentials about the determination of the primary structure of polypeptides.
- To distinguish the structural levels of proteins, and analyse the three-dimensional structure and folding of these biomolecules.
- To set up the relation structure-function of the proteins as essential molecular machines to carry out cellular and intercellular physiological functions.
- To know the characteristics of a biological catalyst.
- To describe the progress curve for an enzymatic reaction and to calculate the specific activity of an enzyme preparation.
- To state the meaning of the kinetic parameters for an enzyme.
- To identify the chiral centres of the monosaccharides and to define the concepts of enantiomer, epimer and anomer.
- To describe the composition and properties of the cellular membrane.
- To set up the nature of the different transport mechanisms through the membrane.
- To explain the phenomenon of denaturation and renaturation of nucleic acids.
- To know the characteristics of the telomeres in linear eukaryotic chromosomes.
- To describe the concept of mutation and to enumerate the mechanisms of DNA repair.
- To explain the concepts of general recombination, specific site recombination and transposition and to mention the main characteristics of their mechanisms.
- To describe the splicing process related to RNA maduration.
- To know the enzymatic activity of the reverse transcriptase and to describe its role in the viral infection process.
- To explain the characteristics of the genetic code.
- To define the concepts of a regulator gene, a repressor, a promoter and an operator (operon), and to describe the control mechanisms in the expression of the lac and trp operons.
- To explain the notion of DNA cloning and to describe the main cloning vectors.